Work Package 3 : Preparation and characterization of green cargo ships


The INTICOSM project aims at the cross-border development of biosourced cargo ships and their use in the field of cosmetic formulation. These biosourced cargo ships will be either dendrimers or polymers. As far as dendrimers are concerned, they are synthetic macromolecular chemistry objects that offer a range of applications both in the medical field (vectorization of active ingredients, therapy, medical imaging) and in the field of catalysis by complexing or stabilizing organic, organometallic complexes, nanoparticles or enzymes. Their size is generally between 1 and 100 nm and these molecules therefore have a controlled structure atom by atom.

From an environmental point of view, dendrimers are real metal or organic molecule traps and also play a decisive role in traditional catalysis processes. Given this panel of applications, it is therefore a true legochemistry (Expression invented by Pierre-Gilles de Gennes) that is at the crossroads of exact sciences such as chemistry, of course, but also materials, drugs, nanosciences in general, biology and medicine.

The current emergence of bio- (or agro-) sourced compounds stems from the depletion of oil resources, the fight against the increase in greenhouse gases and the preservation of the environment, which encourage the search for alternatives to petrochemical products. Thus, obtaining "green" dendrimers from bioresources whose non-food use is targeted (sugars, glycerol) represents a challenge integrating the field of green chemistry and it should be thought that these new dendrimers could be more bio- or eco-compatible.

The biosourced polymers will be made of poly(oxazoline), a well-defined and highly biocompatible class of compounds. The synthetic platform for these compounds offers high flexibility to control the physicochemical properties, thus allowing an adjustment of the properties for the intended encapsulation and release behaviour. The bioresources that will be used for monomer synthesis include aminoethanol from glycerin with various acids (acetic, propionic and undecenoic acid).